Added: Donathan Beran - Date: 26.12.2021 04:57 - Views: 20472 - Clicks: 7495
Background: Ascorbic acid vitamin Cadministered orally in high doses has been observed to relieve pain and reduce opioid use in cancer patients. In vitro studies have also shown that antioxidants, such as vitamin C, may, at high concentrations, inhibit the endogenous opioid degrading metalloenzyme and increase endorphin levels.
In the present study the effects of oral administration of high doses of vitamin C on withdrawal syndrome of heroin abusers were investigated. The on the intensity of withdrawal syndrome WSestimated according to DMS-III criteria, were compared to a third group of heroin addict in-patients group C, 30 males-control grouptreated only by conventional medication. : The patients of the vitamin C-treated groups in-patients and out-patients experienced mild WS in Conclusions: The indicate that high doses of ascorbic acid administered orally, may ameliorate the withdrawal syndrome of heroin addicts.
Further studies are needed in order to estimate the dose- and time-dependent effects of ascorbic acid treatment, and to clarify its mechanisms of action in the withdrawal syndrome. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable.
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of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Cite Display options Display options. Abstract Background: Ascorbic acid vitamin Cadministered orally in high doses has been observed to relieve pain and reduce opioid use in cancer patients. Similar articles [Tizanidine in the treatment of acute withdrawal symptoms in heroin dependent patients].
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Psychopharmacology Berl. Epub Mar PMID: Ibogaine in the treatment of heroin withdrawal. Mash DC, et al. Alkaloids Chem Biol. No abstract available. See all similar articles. Zelfand E. Integr Med Encinitas. Root-Bernstein R, et al. Int J Mol Sci. The role of vitamin C in the treatment of pain: new insights.
Carr AC, et al. J Transl Med. The effect of vitamin C on morphine self-administration in rats. Talkhooncheh M, et al. Adv Biomed Res. Broderick PA. J Neural Transm Vienna. Epub Sep Publication types Clinical Trial Actions. Comparative Study Actions.
MeSH terms Adult Actions. Humans Actions. Male Actions. Outpatients Actions. Single-Blind Method Actions. Treatment Outcome Actions. Substances Analgesics, Opioid Actions. Narcotics Actions. Heroin Actions. Ascorbic Acid Actions. Copy Download.Vitamin c withdrawal
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Vitamins for Opioid Withdrawal